RNA Details
Disease Name
nephritis interstitia
Tissue
kidney
RNA Symbol
mir-34a
RNA ID
MI0000268
RNA Type
miRNA
Alteration Pattern
up regulation
Species
homo sapiens
Detection Methods
NA
Target
SIRT1
Pathway
NA
PubMed ID
29371016
Title
High glucose up-regulates microRNA-34a-5p to aggravate fibrosis by targeting SIRT1 in HK-2 cells
Year
2018
Function
Sirt1 which is vital in the evolution of renal tubulointerstitial fibrosis (TIF) in diabetic nephropathies can be directly suppressed by miR-34a-5p.